Vitalis. Longevity Stack
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Clinical Doses, No Exceptions 1,745mg Active Per Serving No Proprietary Blends Lab Tested & Verified Ships 8/8 30-Day Guarantee Cheap Supplements Are Expensive 1,745mg Active Per Serving Clinical Doses, No Exceptions 1,745mg Active Per Serving No Proprietary Blends Lab Tested & Verified Ships 8/8 30-Day Guarantee Cheap Supplements Are Expensive 1,745mg Active Per Serving
WOLV · Longevity Formula

VITALIS

Outlast Everything.

For the version of you that hasn't been built yet.

Age Slow. Live Bold.

The nine-compound longevity stack dosed at the levels actual research uses. NMN, Trans-Resveratrol, R-ALA, HPLC-verified Astragaloside IV. Not a multivitamin. Not marketing. The molecular foundation for a body that ages slower, runs cleaner, and shows up in your 60s the way most people peak in their 30s.

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90 Capsules · 30 Servings · 3 Daily
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VITALIS (Longevity Matrix)

★★★★★ 4.9 · 36 Reviews
Clinically Dosed·No Added Fillers·No Magnesium Stearate·No Silicon Dioxide·No Proprietary Blends
Included FreeThe Long Game Protocol

$79 for 9 longevity compounds at clinical doses. Or $200+ elsewhere if you bought them separately. Your call.

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01 · Why It Works
The Formula

Built to handle
every angle.

Vitalis isn't one ingredient hoping to do it all. Eleven clinical-range longevity compounds, every dose accountable, every form deliberate. NAD+, senolytics, autophagy, mitochondrial energy. all in one capsule.

🧬

NAD+ Restoration

NMN 500mg. Clinical research dose.

Studies suggest support for NAD+ levels. The coenzyme that drives cellular energy production and declines ~50% by middle age.
🍇

SIRT1 Activation

Trans-Resveratrol 300mg. 99% pure.

The bioactive isomer, no emodin laxative risk. Activates SIRT1, the longevity gene pathway that mimics caloric restriction.
🧹

Senolytic Activity

Quercetin Dihydrate 300mg. Research-validated form.

Studies suggest support for clearing senescent "zombie" cells that drive age-related inflammation.

Mitochondrial Energy

CoQ10 100mg + PQQ 20mg. Fuel + biogenesis.

CoQ10 (Ubiquinone) supports existing mitochondria. PQQ is one of the few compounds that supports mitochondrial biogenesis (creating new ones).
🧠

Cognitive Longevity

Spermidine 5mg. From wheat germ.

The molecule that triggers autophagy, your cells' internal cleanup system. Higher autophagy means healthier cells, longer.
🛡️

Telomere & Antioxidant

Astragalus 5% Astragaloside IV. HPLC verified.

Third-party verifiable, the specific compound studied for telomere maintenance. Not generic "astragalosides" or "polysaccharides" most brands substitute.
02 · The Formula
Supplement Facts

Every ingredient.
Every dose. Shown.

No proprietary blends. No phytosome marketing. Every compound listed, every milligram accounted for. Read it, research it, hold us to it.

Serving Size: 3 Capsules · 30 Servings 1,745mg Total
Cellular Energy · NAD+ Precursor
NMN
500mg · β-Nicotinamide Mononucleotide

Nicotinamide Mononucleotide is the precursor your body uses to make NAD+, the coenzyme essential for cellular energy production. NAD+ levels decline ~50% by middle age. one of the clearest molecular markers of biological aging. Studies on NMN at 250 to 500mg suggest support for NAD+ restoration. We dose at 500mg. the upper end of the research range. half-doses are half-effect.

Dose
500mg
Form
β-NMN
Target
NAD+ Restoration
Best Results
8 to 12 Weeks
Effective Dose Range250mg / 500mg max
Upper-Range Research Dose
Polyphenol · Senolytic Activity
Quercetin
300mg · Dihydrate

A polyphenol found in onions, capers, and red wine. Studies suggest support for senolytic activity. clearing "zombie" cells (senescent cells) that accumulate with age and drive inflammation. We use the Dihydrate form at 300mg. the form used in clinical research. Some brands use "phytosome" versions for marketing reasons. we use the form the science actually validates.

Dose
300mg
Form
Dihydrate
Target
Senolytic Activity
Best Results
8 to 16 Weeks
Effective Dose Range250mg / 1g max
Research-Validated Form
Polyphenol · SIRT1 Activator
Trans-Resveratrol
300mg · 99% Trans-Isomer

The polyphenol that made red wine famous. except you'd need to drink 1,000+ glasses for a clinical dose. Resveratrol activates SIRT1, the longevity gene pathway that mimics caloric restriction. Critical: we use 99% Trans-Resveratrol (the bioactive isomer), not 50% which contains 1.4% emodin. a compound with mild laxative effects at 300mg doses. The cheap version costs your gut.

Dose
300mg
Standardization
99% Trans-Isomer
Target
SIRT1 Activation
Pairs With
NMN
Effective Dose Range250mg / 500mg max
99% Pure Trans-Isomer
Adaptogen · Telomere Support
Astragalus Extract
250mg · 5% Astragaloside IV HPLC

Used in Traditional Chinese Medicine for over 2,000 years. Modern research focuses on Astragaloside IV. the specific astragaloside that studies suggest supports telomere maintenance through telomerase activation. Telomeres are the protective caps on your chromosomes that shorten with each cell division. Shorter telomeres = older cells. We standardize to 5% Astragaloside IV by HPLC, third-party verifiable. not generic "astragalosides" or "polysaccharides" which most brands quietly substitute.

Dose
250mg
Standardization
5% Astragaloside IV HPLC
Target
Telomere Maintenance
Best Results
12+ Weeks
Effective Dose Range200mg / 500mg max
5% Astragaloside IV HPLC
Antioxidant · Mitochondrial
Alpha Lipoic Acid
250mg · R-ALA Isomer

A mitochondrial antioxidant that recycles other antioxidants (Vitamin C, E, glutathione). a multiplier for your entire antioxidant system. Also supports glucose metabolism and insulin sensitivity. We use the R-isomer (R-ALA). the biologically active form your body actually uses, not the cheaper racemic 50/50 mix (R+S-ALA) that most brands quietly substitute. At 250mg of R-ALA, you get the active load of ~500mg of racemic ALA.

Dose
250mg
Target
Antioxidant Recycling
Function
Mitochondrial
Best Results
4 to 8 Weeks
Effective Dose Range200mg / 600mg max
R-Isomer (Bioactive Form)
Coenzyme · Mitochondrial Energy
CoQ10
100mg · Ubiquinone

The spark plug of your mitochondria. the molecule that moves electrons through the energy production chain. CoQ10 levels decline with age and with statin use. We use the Ubiquinone form at 100mg, the most-studied dose. Ubiquinol is marketed as "better" but conversion in healthy adults is efficient enough that Ubiquinone is what longevity research overwhelmingly uses.

Dose
100mg
Form
Ubiquinone
Target
Mitochondrial Energy
Best Results
4 to 8 Weeks
Effective Dose Range100mg / 300mg max
Most-Studied Form
Quinone · Mitochondrial Biogenesis
PQQ
20mg · Pyrroloquinoline Quinone

One of the only known compounds that supports mitochondrial biogenesis. the actual creation of new mitochondria. Most longevity ingredients support existing mitochondria. PQQ helps you build more. At 20mg per serving, the dose used in published research. rare in supplements where most brands use 5 to 10mg.

Dose
20mg
Target
Mitochondrial Biogenesis
Pairs With
CoQ10
Best Results
8+ Weeks
Effective Dose Range10mg / 40mg max
Research Dose
Polyamine · Autophagy Trigger
Spermidine
5mg · Wheat Germ-Derived

The molecule that triggers autophagy. your cells' internal recycling and cleanup system. Higher autophagy = healthier cells. Studies on spermidine suggest support for cellular renewal, cardiovascular function, and cognitive health in aging. We source from wheat germ. the most concentrated natural form.

Dose
5mg
Source
Wheat Germ
Target
Autophagy
Best Results
8+ Weeks
Effective Dose Range1mg / 6mg max
Wheat Germ-Derived
Processing Aid · Clean Manufacturing
Nu-Flow
20mg · Organic Rice Hulls

Organic rice hull concentrate. Same machinery function as magnesium stearate or silicon dioxide, no synthetic excipients.

Dose
20mg
Source
Organic Rice Hulls
Function
Natural Flow Agent
Free From
Mag Stearate / SiO₂
Clean Manufacturing

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

03 · The Timeline
What to expect

Day one to
month three.

Vitalis is not a switch. it's a 5-year decision. Longevity compounds work invisibly at the cellular level. The math compounds over months and years. Here's the honest timeline.

Days 1–30 · Cellular Foundation

Subtle, but building.

NMN, Resveratrol, ALA, and CoQ10 begin restoring NAD+ levels and mitochondrial function. Most users don't "feel" anything dramatic. What's happening is invisible: your cells are functioning closer to their younger baseline. Trust the math.

NMNNAD+Mitochondria
Months 1–3 · Compounding Effects

Energy and recovery improving.

Subtle but real. Workout recovery is faster. Mental clarity is sharper in the afternoons. Skin quality may improve. These aren't feel-it-immediately products. they're foundational. The biological markers are shifting; the subjective experience follows.

Cellular EnergyRecoveryCompounding
Months 3–6 · Telomere & Autophagy

Slower decline.

Astragalus, Spermidine, and the senolytic compounds (Quercetin, Resveratrol) are doing their long-game work. supporting telomere maintenance and cellular renewal. By month 6, biological age testing (if you do it) often shows improvement vs. baseline.

TelomeresAutophagyLong-Term
Months 6+ · The Long Game

A 5-year decision, not a 5-day one.

Vitalis is a long-term commitment. The research on these compounds suggests benefits that compound over years, not weeks. You're not taking Vitalis to feel different tomorrow. You're taking it because you want to be sharper, stronger, and healthier in 5 years than the trajectory you're currently on.

LongevityLong-TermInvestment
04 · The Comparison
VITALIS vs. The Market

See what you're
actually buying.

Most longevity brands either single-ingredient at clinical doses or multi-ingredient at sub-clinical "sprinkle" doses. We don't. The numbers tell you what you're actually paying for. or, more often, what you're not.

Feature WOLV VITALIS Basic NMN Brand Premium Longevity Stack
NMN 500mg 250–500mg 300mg (NR instead)
Trans-Resveratrol 300mg (99%) 250–500mg (50%)
Quercetin 500mg 250mg
Astragalus 300mg (astragalosides)
Spermidine 5mg ✓
PQQ 20mg 10mg
Astragalus Standardization 5% Astragaloside IV HPLC ✗ or generic Polysaccharides only
Total Longevity Compounds 9 1 4 to 5
Total Active Per Serving 1,745mg ~500mg ~1,300mg
The Real Cost of Cheap

Cheap supplements
are expensive.

Here's the math.

Buying NMN, Trans-Resveratrol, Quercetin, CoQ10, PQQ, Astragalus (5% Astragaloside IV), R-ALA, and Spermidine separately at clinical doses costs $200+ per month. A $50 NMN-only supplement at 250mg is more expensive than $79 Vitalis with 9 longevity compounds at clinical doses. You're paying for one ingredient at half the dose instead of the integrated stack the research actually supports.

We dose at the levels used in published research. We standardize every active ingredient. We list every milligram on the label. There are no proprietary blends to hide behind, no fairy-dust micrograms designed to look impressive next to ingredients that actually work.

You can pay less for a bottle that doesn't do anything. Or you can pay what real doses actually cost. We don't blame anyone for the first choice. most people don't know the difference. But once you do, the math only goes one way.

500mg
NMN at researched dose
0mg
Hidden in proprietary blends
1,745mg
Active ingredients per serving
05 · Our Standard
What We Won't Compromise

Built different.
Held to it.

Zero Proprietary Blends. Ever.

Every dose is listed. Every ingredient is accountable. A proprietary blend is where brands hide underdosed ingredients behind a marketing name. We don't do that.

Clinical-Range Doses Only

We looked at the published research on every ingredient. We dosed at or near what the studies actually used. Not the minimum that lets us put it on the label. The dose that works.

Third-Party Lab Tested

Every batch is verified by an independent lab before it ships. Every dose listed, every milligram accounted for. Certificate of Analysis available on request.

Form Matters. We Chose the Best.

Trans-Resveratrol at 99% pure, not 50% with emodin laxative risk. Quercetin Dihydrate (research-validated form), not phytosome marketing. CoQ10 as Ubiquinone (most-studied form), not Ubiquinol. R-ALA isomer (the bioactive form), not the cheap racemic 50/50 mix. Astragalus standardized to 5% Astragaloside IV by HPLC, not generic polysaccharides. Every form decision was deliberate, not cheap.

No Added Fillers. Honest Carrier.

No magnesium stearate. No silicon dioxide. No artificial flow agents. Where our standardized extracts need a carrier to stabilize, we use a trace of maltodextrin, and we list it, because we list everything. Full disclosure. Nothing hidden in the small print.

From the Founder
Patrick Kane, Founder of WOLV

"Longevity isn't sexy. No instant feel. But the math matters. NAD+ levels decline 50% by middle age and that decline drives everything else. Vitalis is the formula I'd build if I was buying ingredients separately. No proprietary blends. No fillers. No BS. This is a 5-year decision, and I'm in."

Patrick Kane
Founder, WOLV
Daily Protocol

How to take
it.

Simple. Consistent. Daily.

When

3 capsules with food in the morning. Some users split the dose (2 in morning, 1 with lunch) to extend coverage. Take with food to support absorption of fat-soluble compounds (Resveratrol, CoQ10, R-ALA).

How Long

Honest answer: probably not in the first 30 days. Longevity compounds work at the cellular level. NAD+ restoration, telomere maintenance, autophagy. none of which produce dramatic subjective effects. By month 2 to 3, most users notice better recovery, mental clarity, and energy. By month 6+, the long-term benefits compound. This is a 5-year decision, not a 5-day one.

Who Shouldn't

Pregnant or nursing women, anyone under 18, anyone on chemotherapy or anti-coagulant medications, anyone with severe iron-overload conditions (resveratrol can interact), or anyone on prescription methylation-affecting medications should consult a physician before use. We strongly recommend pairing Vitalis with annual blood work.

06 · The Pack Speaks
Real Reviews. From Day One.

Tested.
Reviewed.

Before we launched as WOLV, we were HOWL. We sent Vitalis to our OGs first. People playing the long game. These are their unedited reviews. No paid sponsorships. No filters. Verified customer reviews land here as orders ship.

HOWL ORIGINAL
★★★★★

Most longevity stuff out there is sprinkles in a bottle and clever marketing. This one isn't messing around. Doses you'd actually trust.

SUE N., PARK CITY, UT
HOWL ORIGINAL
★★★★★

i'm 47. my blood work is better than it was at 42. that's all the proof i need lol

PATTI C., DENVER, CO
HOWL ORIGINAL
★★★★★

Bryan Johnson longevity stack but at a price normal people can do. Not a feel-it-instantly product. This is a play-the-long-game move.

HEIDI M., AUSTIN, TX
HOWL ORIGINAL
★★★★★

been with patrick since the howl days. the considered formulation here is the most considered yet. you can tell the care.

YULIYA P., NASHVILLE, TN
HOWL ORIGINAL
★★★★

Long-term play, don't expect instant feel. Three months in, my energy is steadier and my recovery is way faster. Solid foundation.

MINA B.
HOWL ORIGINAL
★★★★★

My naturopath asked for the label. She approved every ingredient. Said the doses are the gold standard.

CAROLINE M., ASHEVILLE, NC
HOWL ORIGINAL
★★★★★

i'm 52. wife is 50. we both take it. our biological age scores both dropped 3 years. wild.

SHALEY T., PORTLAND, OR
HOWL ORIGINAL
★★★★

Excellent formula. The cost is steep but a fraction of building this stack from individual bottles. Worth it.

SAM G., BOULDER, CO
HOWL ORIGINAL
★★★★★

The ingredients work together properly, not just thrown in. Most brands miss this. Patrick clearly thought it through.

DIEGO R., SUN VALLEY, ID
HOWL ORIGINAL
★★★★★

Daily ritual now. Take it with breakfast. Three months in, my recovery and energy are the best they've been in a decade.

KIM M., SALT LAKE, UT
HOWL ORIGINAL
★★★★

Honest review: not instantly noticeable. The math compounds over months. Worth the long view. Auto-shipping.

LUCA M., MAMMOTH, CA
07 · Your Voice
Write a Review

You're the Pack
now.

We heard from our OG subscribers above. Now we want to hear from you. Real customer reviews land here and help the next Pack member decide. Drop a star rating and tell us how the formula landed.

Customer Reviews

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08 · Questions
Cleared Up

Honest answers.
No fine print.

When will I feel VITALIS working?

Honest answer: probably not in the first 30 days. Longevity compounds work at the cellular level. NAD+ restoration, telomere maintenance, autophagy. none of which produce dramatic subjective effects. By month 2 to 3, most users notice better recovery, mental clarity, and energy. By month 6+, the long-term benefits compound. This is a 5-year decision, not a 5-day one.

Why not just buy NMN separately?

You can. But NMN works best with Resveratrol (which activates SIRT1, the gene NAD+ feeds), Quercetin (which supports senolytic activity), and CoQ10 (which uses NAD+ in mitochondrial energy production). Buying these separately costs $200+ per month at clinical doses. Vitalis is the integrated stack at a price that makes the math work.

Can I take it forever?

Yes. All ingredients are safe for long-term daily use at these doses. We'd recommend annual blood work to track your biomarkers, but you don't need to cycle Vitalis.

Should I stack this with Aware Wolf?

Yes. Aware Wolf supports acute cognitive performance. Vitalis supports long-term cognitive longevity. They work on different timescales and don't overlap.

Should I stack with Creatine Matrix?

Yes. strongly recommended. NMN methylates in your body, which uses methyl groups. The betaine (TMG) in Creatine Matrix replenishes methyl group reserves. They're better together than separately.

Is the Trans-Resveratrol the same as the cheap stuff?

No. Cheap resveratrol is 50% standardization which contains 1.4% emodin. a compound with mild laxative effects at 300mg doses. We use 99% Pure Trans-Resveratrol. the bioactive isomer, no emodin issues. The cheap version costs your gut.

What's your return policy?

30 days, no questions, no hassle. We'll be honest. judging Vitalis on 30 days is like judging compound interest on a single deposit. But if you want to send it back, we'll refund you.

The Pack Waits

Slower decline.
Sharper baseline.

1,745mg of clinical doses across 9 longevity compounds. NAD+ support. Senolytics. Mitochondrial energy. Autophagy. Telomere maintenance. Daily. and the trajectory you're on starts bending toward something better.

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